Seroepidemiological Evidence that Shearing Wounds are Mainly Responsible for Corynebacterium pseudotuberculosis Infection in Sheep.

An improved Corynebacterium pseudotuberculosis vaccine for sheep.

Extensive experiments in mice confirmed that the immunogenicity of a Corynebacterium pseudotuberculosis vaccine could not be significantly improved with the use of various adjuvants. Immunity against C. pseudotuberculosis likewise could not be enhanced by incorporating various immunostimulants into the vaccine or by the use of live vaccines. However, a combination of aluminium hydroxide gel and...

Corynebacterium pseudotuberculosis infection in a butcher.

omas, and is limited to the cranial-spinal axis, without systemic disease. A known high-risk group for PCNSL comprises patients with immunosuppression, but in the last 15-20 years there has been a threefold increase in patients who are immunocompetent, and the causative factors for this increase are unknown [l-31. PCNSL commonly presents as a rapidly space-occupying lesion. Rarely, patients wit...

Identification of a novel antigen from Corynebacterium pseudotuberculosis that protects sheep against caseous lymphadenitis.

A 40-kDa protein antigen from Corynebacterium pseudotuberculosis has been identified by application of a strategy that employs locally derived antibody-secreting cells (ASC). ASC probes generated by culture of ASC obtained from the lymph node draining the site of infection showed a specificity restricted to a 40-kDa antigen. Analysis of immunoblots with sequential serum samples taken from sheep...

Seroepidemiological studies of Borrelia burgdorferi infection in sheep in Norway.

An enzyme-linked immunosorbent assay for antibodies to Borrelia burgdorferi in sheep was established. The assay was used in a seroepidemiological survey in which serum samples from 327 Norwegian rams were screened for antibodies to B. burgdorferi. These rams were randomly chosen, clinically healthy animals from all parts of Norway. They came both from areas where Ixodes ricinus is common and fr...

Isolation of Corynebacterium pseudotuberculosis from Camel in Iran